3,4-Dimethoxybenzenesulphonyl chloride
3,4-Dimethoxybenzenesulfonyl chloride
CAS: 23095-31-0
Molecular Formula: C8H9ClO4S
3,4-Dimethoxybenzenesulphonyl chloride - Names and Identifiers
| Name | 3,4-Dimethoxybenzenesulfonyl chloride |
| Synonyms | AKOS B019393 ASISCHEM D48920 AKOS BBS-00006964 ART-CHEM-BB B019393 TIMTEC-BB SBB003242 3,4-Dimethoxybenzenesulfonyl chloride 3,4-DIMETHOXYBENZENESULFONYL CHLORIDE 3,4-Dimethoxybenzenesulphonyl chloride 3,4-DIMETHOXYBENZENESULPHONYL CHLORIDE |
| CAS | 23095-31-0 |
| InChI | InChI=1/C8H9ClO4S/c1-12-7-4-3-6(14(9,10)11)5-8(7)13-2/h3-5H,1-2H3 |
| InChIKey | RSJSYCZYQNJQPY-UHFFFAOYSA-N |
3,4-Dimethoxybenzenesulphonyl chloride - Physico-chemical Properties
| Molecular Formula | C8H9ClO4S |
| Molar Mass | 236.67 |
| Density | 1.359±0.06 g/cm3(Predicted) |
| Melting Point | 67-70 °C (lit.) |
| Boling Point | 346.2±27.0 °C(Predicted) |
| Flash Point | 163.2°C |
| Vapor Presure | 0.000117mmHg at 25°C |
| Appearance | Crystalline Powder |
| Color | Off-white to beige |
| BRN | 2840170 |
| Storage Condition | 2-8°C |
| Sensitive | Moisture Sensitive |
| Refractive Index | 1.522 |
3,4-Dimethoxybenzenesulphonyl chloride - Risk and Safety
| Risk Codes | 34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 3261 8/PG 2 |
| WGK Germany | 3 |
| HS Code | 29049090 |
| Hazard Note | Corrosive |
| Hazard Class | 8 |
| Packing Group | II |
3,4-Dimethoxybenzenesulphonyl chloride - Introduction
chloride is an organic compound with the chemical formula C8H9ClO3S. Its main properties are as follows:
1. Appearance: 3, chloride is a white crystalline solid.
2. Solubility: It has good solubility in common organic solvents such as ether, methanol and dichloromethane.
3. Reactivity: It is an acid chloride compound, which can undergo acyl substitution reaction, and often reacts with amine compounds to generate the corresponding amide derivatives.
3, the main uses of chloride are as follows:
1. Organic synthesis: It is a commonly used organic synthesis reagent, which can be used to synthesize various amide derivatives, such as drugs, pesticides and dyes.
2. Protecting group: it can be used as a reagent to protect the hydroxyl group, and it can protect the hydroxyl group from the reaction in organic synthesis.
3, the preparation method of chloride is generally obtained by The chlorination reaction of 3,4-dimethoxybenzene sulfonic acid. The specific steps are as follows:
1. Dissolve 3,4-dimethoxybenzenesulfonic acid under acidic conditions, such as adding a small amount of hydrochloric acid in dichloromethane or benzene.
2. Under the condition of stirring, slowly add thionyl chloride to the reaction system, and keep the temperature at 0-5 degrees Celsius.
3. After the reaction is completed, the target product 3, chloride, is obtained by filtration or crystallization.
In the process of using 3 chloride, you need to pay attention to the following safety information:
1. It is necessary to operate in a well-ventilated laboratory environment to avoid inhalation of aerosols or contact with skin.
2. Wear appropriate personal protective equipment, such as chemical gloves, laboratory glasses and protective face masks.
3. Avoid contact with water or moisture to prevent the generation of corrosive gases.
4. Storage should be sealed, away from the fire and flammable materials.
5. When handling the compound, the relevant safety procedures and regulations should be observed.
1. Appearance: 3, chloride is a white crystalline solid.
2. Solubility: It has good solubility in common organic solvents such as ether, methanol and dichloromethane.
3. Reactivity: It is an acid chloride compound, which can undergo acyl substitution reaction, and often reacts with amine compounds to generate the corresponding amide derivatives.
3, the main uses of chloride are as follows:
1. Organic synthesis: It is a commonly used organic synthesis reagent, which can be used to synthesize various amide derivatives, such as drugs, pesticides and dyes.
2. Protecting group: it can be used as a reagent to protect the hydroxyl group, and it can protect the hydroxyl group from the reaction in organic synthesis.
3, the preparation method of chloride is generally obtained by The chlorination reaction of 3,4-dimethoxybenzene sulfonic acid. The specific steps are as follows:
1. Dissolve 3,4-dimethoxybenzenesulfonic acid under acidic conditions, such as adding a small amount of hydrochloric acid in dichloromethane or benzene.
2. Under the condition of stirring, slowly add thionyl chloride to the reaction system, and keep the temperature at 0-5 degrees Celsius.
3. After the reaction is completed, the target product 3, chloride, is obtained by filtration or crystallization.
In the process of using 3 chloride, you need to pay attention to the following safety information:
1. It is necessary to operate in a well-ventilated laboratory environment to avoid inhalation of aerosols or contact with skin.
2. Wear appropriate personal protective equipment, such as chemical gloves, laboratory glasses and protective face masks.
3. Avoid contact with water or moisture to prevent the generation of corrosive gases.
4. Storage should be sealed, away from the fire and flammable materials.
5. When handling the compound, the relevant safety procedures and regulations should be observed.
Last Update：2024-04-09 21:21:28
